About the Condition | TAVNEOS® (avacopan)

Approved Use: TAVNEOS® is a prescription medicine that is used with other medicines (such as glucocorticoids) to treat adults with severe

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Approved Use: TAVNEOS® is a prescription medicine that is used with other medicines (such as glucocorticoids) to treat adults with severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis [GPA], formerly known as Wegener’s granulomatosis, and microscopic polyangiitis [MPA]). It is not known if TAVNEOS is safe and effective in children under the age of 18.

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What is severe active ANCA-associated vasculitis (AAV)?

AAV is a group of rare diseases that affects small- to medium-sized blood vessels in your body

These diseases involve inflammation of the blood vessels, which reduces blood flow and could lead to impaired organ function. While your genetics and environment are thought to be contributing causes of these diseases, the exact cause isn’t known yet.

Active disease means that you have signs and/or symptoms of the disease that are new, not getting better, or getting worse.

Severe disease is defined as AAV with signs and/or symptoms that are organ- or life-threatening.

Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are the 2 most common types of AAV

Severe active GPA and MPA are serious but treatable diseases. Your doctor will work with you to develop a treatment plan that suits your needs.

granulomatosis-with-polyangiitis-mb

Granulomatosis with polyangiitis (GPA)

GPA happens when immune cells clump together, forming what are known as granulomas. This causes inflammation in the blood vessels. It can affect the whole body, but often affects the kidneys, lungs, sinuses, nose, ears, and throat.

Kidneys Lungs Nose Ears

Microscopic polyangiitis (MPA)

MPA shares many symptoms with GPA, but can have a more severe impact on the kidneys. People with MPA may be at a higher risk of uncontrolled bleeding in their lungs.

Kidneys Lungs

Identifying the signs and symptoms of severe active GPA or MPA early can lead to a timely diagnosis that can help you and your doctor decide on a treatment plan to help manage your condition.

What are the signs and symptoms?

Talk to your doctor if you are having issues in any of the areas listed below:*

Tap each body part to learn more